2026-09-24
20 分钟If you're over 60 and experiencing vision loss, it's likely you have age-related macular degeneration, or AMD.
AMD blurs your central vision and makes it difficult to see details straight in front of you.
It's also the leading cause of blindness in people over the age of 65. Here,
we'll talk about wet AMD, which affects 10-15% of patients with AMD.
It also accounts for more severe AMD-related vision loss compared to dry AMD.
Scientific American Custom Media recently sat down with Dr. Praveen Dougal,
Ocular Therapeutics CEO, to explore what has changed and how we understand wet AMD,
where unmet needs remain, and what kind of experimental treatments are on the horizon.
Welcome, Dr. Praveen Dougal.
It's so great to have you on the podcast.
Megan, thank you for the opportunity.
It's lovely to be here.
So we're here to talk about your treatment in...
Development, which is known as OTXTKI.
But before we talk about that, let's make sure all of our listeners are on the same page.
Will you first just explain how age-related macular degeneration affects our vision?
What's happening in the eye when people are experiencing this vision problem?
The retina is kind of like a shape, like a cup, if you will.
And in the center of that cup is an area that we call the macula.
The macula is where we see fine, detailed vision from,