Can magic mushrooms help treat anorexia?

神奇蘑菇能帮助治疗厌食症吗?

Science Quickly

2026-08-21

24 分钟
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A small clinical trial suggests that psilocybin, the psychedelic compound in magic mushrooms, may help some people with anorexia when combined with intensive therapy. Science Quickly host Rachel Feltman speaks with health journalist Alexandra Pattillo about what early research has found, why scientists think psychedelics could help loosen the rigid thought patterns associated with eating disorders, and why experts say larger studies are needed before the treatment can be considered a proven option Recommended Reading: Could psilocybin be the key to treating anorexia?  Americans are increasingly open to using psychedelics for medical reasons Trump’s psychedelics executive order could accelerate new treatments—including for children E-mail us at sciencequickly@sciam.com if you have any questions, comments or ideas for stories we should cover! Discover something new everyday: subscribe to Scientific American and sign up for Today in Science, our daily newsletter. Science Quickly is produced by Rachel Feltman, Fonda Mwangi and Jeff DelViscio. This episode was edited by Alex Sugiura, with fact-checking by Marielle Issa and Aaron Shattuck. Our theme music was composed by Dominic Smith. Learn more about your ad choices. Visit megaphone.fm/adchoices
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  • I didn't like what you said, Odin pauses, about the future.

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  • Written and read by me, Curtis Garner.

  • Listen to the free audiobook now.

  • For Scientific American Science Quickly, I'm Rachel Heltman.

  • I have a quick content note before we begin.

  • This episode features discussion of eating disorders.

  • We'll include some relevant resources at the end of the episode.

  • According to a 2020 report, as much as 9% of the US population,

  • which is nearly 31 million people, will have some kind of eating disorder during their lifetime.

  • That same study found that someone dies as a direct consequence of an eating disorder every 52 minutes.

  • Anorexia nervosa, an eating disorder defined by strict restriction of one's food intake, is particularly fatal.

  • Approximately 5% of patients die within four years of diagnosis.

  • In addition to a suicide rate 18 times higher than that of the general population,

  • people with anorexia nervosa are at high risk of organ damage and other consequences of malnutrition,

  • which can increase their risk of death even years after entering remission.

  • At least part of what makes eating disorders so deadly is that, frankly, we're not great at treating them.

  • While psychiatric interventions like cognitive behavioral therapy and antidepressants make a huge difference for some,

  • research suggests that around half of patients won't achieve sustained recovery.

  • That lets scientists to explore an unconventional treatment option, psychedelic mushrooms.