2026-09-07
2 小时 3 分钟There's a widely accepted hypothesis that mitochondria with excess energy leads to problems.
Many people that are listening have probably heard of reactive oxygen species.
This is forms of oxygen that become reactive and end up spinning out and damaging proteins and nucleic acids.
And I think it is widely accepted that one of the contributors to that is mitochondria that have too much.
Basically, the form that energy takes when it's extracted
from the food we eat and before it's converted to ATP is powering the mitochondria.
And when that mitochondria is overpowered,
that leads to a state that is very susceptible to generation of these reactive species
that end up damaging our genome, creating mutations and damaging proteins and creating many of the problems that we see.
Welcome to the Huberman Lab podcast, where we discuss science and science-based tools for everyday life.
I'm Andrew Huberman, and I'm a professor of neurobiology and ophthalmology at Stanford School of Medicine.
My guest today is Dr. Jared Rutter.
Dr. Jared Rutter is a professor
of biochemistry at University of Utah and an investigator with the Howard Hughes Medical Institute.
He is one of the world's top experts in the biology of mitochondria and metabolism.
Mitochondria are known as the powerhouse of the cell.
But as you'll learn today, they do far more than just power our cells.
They also determine how much energy goes into making new cells to making
sure that cells stay healthy and to fighting off disease.
Today's conversation explains how mitochondria do that and clarifies what your metabolism really is.