GLP-1 drugs are entering a new chapter

GLP-1类药物正开启新的篇章。

Science Quickly

2026-03-18

15 分钟
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In this episode of Science Quickly, Scientific American’s associate health editor Lauren Young joins host Kendra Pierre-Louis to talk about how the story of GLP‑1 drugs such as Ozempic, Wegovy and Mounjaro is evolving. We trace GLP-1s’ origins as type 2 diabetes treatments, their rise as blockbuster weight‑loss medications and the ensuing complications—including the expanding market for compounded drugs. And we look at how the landscape has only grown more complex as researchers explore surprising potential uses for GLP‑1s, from addiction treatment to cardiovascular benefits, even as new concerns emerge about long‑term effects. Recommended Reading: Compound weight-loss drugs are everywhere. The FDA is cracking down People who took GLP-1 drugs had lower risk of all kinds of drug and alcohol addiction E-mail us at sciencequickly@sciam.com if you have any questions, comments or ideas for stories we should cover! Discover something new everyday: subscribe to Scientific American and sign up for Today in Science, our daily newsletter. Science Quickly is produced by Kendra Pierre-Louis, Fonda Mwangi, Sushmita Pathak and Jeff DelViscio. This episode was edited by Alex Sugiura, with fact-checking by Shayna Posses and Aaron Shattuck. Our theme music was composed by Dominic Smith. Learn more about your ad choices. Visit megaphone.fm/adchoices
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  • This episode is brought to you by Focus Features.

  • On March 27th, Focus Features invites you

  • to be a part of the most explosive movie of this year's Sundance and South by Southwest Film Festivals.

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  • The AI Doc or How I Became an Apocalypse rated PG-13 only in theaters March 27th.

  • For Scientific American Science Quickly, I'm Kendra Peer-Lewis in for Rachel Feldman.

  • In early March, the U.S.

  • Food and Drug Administration sent a warning letter to Novo Nordisk, the maker of Ozympic and Mugovie,

  • saying the company had failed to disclose potential risks associated with taking these drugs.

  • The agency alleged that Novo Nordisk failed a proper report and or follow-up on three deaths of individuals

  • who were taking somaglotide, the key ingredient in Ozympica mogovii.

  • The drugs are part of a broader class of medicine, known as GLP-1s,

  • that have grown wildly popular for everything from type 2 diabetes to weight loss and are increasingly seen

  • as having potential benefits far beyond those two conditions.

  • The popularity of these drugs has led to a sea of GLP-1 offerings flooding the market.

  • Not all of them FDA approved.

  • We sat down with Lauren Young, an associate editor covering health and medicine for Scientific American,

  • to talk about where GLP-1s go from here.

  • Thank you for being here, Lauren.