People are running their own experiments with GLP-1s — with stunning results

人们正在自行进行GLP-1s的实验——结果令人震惊。

Apple News In Conversation

2026-07-17

25 分钟
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GLP-1 drugs like Ozempic and Wegovy are being taken by millions of Americans. These medications have been approved for treating diabetes, obesity, and a small number of other chronic conditions. But even as experts are still learning how the drugs work, many people have found that they help with other disorders — from addiction to brain fog to arthritis — where anecdotal evidence is promising but the formal research hasn’t caught up. Julia Belluz, a contributing writer for the New York Times Opinion section and coauthor of Food Intelligence, joins Apple News In Conversation guest host David Greene to explain why what’s unfolding right now may be the largest uncontrolled drug experiment in modern history.
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  • This is In Conversation from Apple News.

  • I'm David Green in for Shamita Besu.

  • Today, the GLP-1 experiment happening in real time.

  • Millions of people in the U.S.

  • Are taking GLP-1 medications right now, an estimated one in eight adults.

  • You probably know these drugs by their brand names, Ozempic, Wagovi, Manjaro, and Zepbound, just to name a few.

  • GLP-1-based drugs have been around for years and were originally intended for treating diabetes, but they exploded

  • in use when researchers discovered they could cause significant weight loss and were approved for treating obesity.

  • But people are now reporting improvements across a remarkably wide range of other conditions as well,

  • from addiction to concussion symptoms to fertility, most of which have yet to be formally studied.

  • The landscape is changing so fast.

  • There's new drugs coming on all the time.

  • And we're learning in real time what these drugs are doing.

  • That is Julia Baluz.

  • She's a contributing opinion writer to the New York Times and co-author of the book Food Intelligence,

  • the Science of How Food Both Nourishes and Harms Us.

  • Julia has been reporting on GLP-1s for years,

  • so I wanted to have her on the show to take stock of this moment.

  • What has changed since these drugs became a cultural phenomenon?

  • What the evidence shows and still cannot answer?