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The Great Detectives Present Yours Truly Johnny Dollar (Old Time Radio)

2026-03-15

28 分钟
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Introducing Capital, Courage, and Clinical Execution: Lessons from a Biotech Founder-CEO from Clinical Trialblazers. Follow the show: Clinical Trialblazers Clinical Trialblazers is back for Season Two. Host Alberto Grignolo speaks with Paul Garofolo, Co-Founder and CEO of Locus Biosciences, about the leadership mindset behind capital efficiency, resource prioritization, and disciplined execution. Drawing on Paul’s journey from global leadership roles at Patheon to founding a next-generation precision medicine company, this episode explores fundraising across market cycles, founder-friendly capital, strategic and government partnerships, and the science behind Locus’ bacteriophage-based platform aimed at tackling multidrug-resistant infections. DISCLAIMER: Please note, this is an independent podcast episode not affiliated with, endorsed by, or produced in conjunction with the host podcast feed or any of its media entities. The views and opinions expressed in this episode are solely those of the creators and guests. For any concerns, please reach out to team@podroll.fm.
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  • Hello, and welcome back to Clinical Trial Blazers, a podcast by Paracel Biotech,

  • where we explore the human stories behind breakthrough clinical research.

  • I am your host, Alberto Grignolo, and we're excited to kick off Season 2.

  • Today's guest is Paul Garofalo, the co-founder and chief executive officer of Locus Biosciences,

  • a biotechnology company focused on the discovery and development of a next-generation platform

  • for programmed cell death.

  • We'll get more into the science of this in our conversation.

  • Paul's journey to CEO reflects that rare blend of technical training and enterprise-scale operational leadership.

  • Prior to founding Locus, he spent many years at Patheon Pharmaceuticals,

  • where he served in a number of high-profile roles,

  • including Chief Technology Officer and Global Head of Operations for Pharmaceutical Development Services.

  • At Patheon, he led global organizations spanning development,

  • manufacturing, and technology transformation,

  • experiences that continue to shape his views on scalability,

  • capital efficiency, and disciplined execution.

  • Paul is trained in management information systems,

  • and he brings a systems-oriented mindset to his work,

  • whether he is building first-in-class platforms,

  • raising capital across market cycles, or making hard prioritization decisions.

  • Paul joins us today to explore the human and strategic dimensions of funding,