The Cancer Vaccine That Could Save Moderna

可能拯救莫德纳的现代癌症疫苗

The Journal.

2026-08-29

25 分钟
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单集简介 ...

For years, Moderna was a one-hit wonder, a company that bet everything on mRNA, struck gold with a COVID vaccine and then watched its stock crater as the pandemic faded. Now, the company may have found a way to fight skin cancer. An experimental mRNA-based vaccine succeeded in preventing melanoma from returning in high-risk patients, sending drug industry stocks soaring. WSJ’s Xavier Martinez traces Moderna’s wild ride from scrappy startup to the frontier of can treatment. Ryan Knutson hosts. Further Listening: - The FDA Commissioner on Vaccines and Public Trust - The Creator of the Record-Setting Covid Vaccine Sign up for WSJ’s free What’s News newsletter. Learn more about your ad choices. Visit megaphone.fm/adchoices
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  • The biotech company Moderna is best known for its COVID vaccine.

  • The vaccine put the small startup on the map and made it billions of dollars.

  • But in recent years, its business has been in deep trouble.

  • COVID starts to sort of wind down in terms of the urgency that we're treating it with.

  • Sales start to drop in the U.S.

  • Because not as many people are getting vaccinated.

  • That's our colleague Xavier Martinez, who covers biotech.

  • And before you know it, their stock has really bottomed out.

  • It's gone down more than 90% from its peak.

  • You know, the company is bleeding cash.

  • You look at the stock chart and it just looks like the tallest mountain in the world.

  • But earlier this month, Moderna made a surprising announcement.

  • I remember where I was.

  • I was on a call with a different company, with a different pharmaceutical company earlier this month.

  • And I was in the office in a little meeting room.

  • And my editor comes over and starts waving her hands up and down.

  • And clearly something is happening.

  • Hang up the phone now.

  • There's breaking news.

  • Exactly, exactly.