Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

《基础之道:如何优化荷尔蒙以增进健康与活力 | 凯尔·吉尔莱特博士》

Huberman Lab

2025-12-25

42 分钟
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In this Huberman Lab Essentials episode, my guest is Dr. Kyle Gillett, MD, a dual board-certified physician in family medicine and obesity medicine and an expert in optimizing hormone levels to improve overall health. We explain how to improve hormone levels across the lifespan in both men and women using behavioral, nutritional and exercise-based tools. We also discuss common clinical topics, including hormone testing, PCOS, hair loss, testosterone replacement therapy (TRT) and peptides, focusing on potential benefits, tradeoffs and risks. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Maui Nui: https://mauinuivenison.com/huberman Function: https://functionhealth.com/huberman Timestamps (00:00:00) Kyle Gillett (00:00:36) Hormone Health; Women vs Men, Tool: Hormone Testing (00:02:35) Tool: Big 6 Lifestyle Pillars to Optimize Hormone Health (00:04:32) Sponsor: AG1 (00:06:17) Diet, Individualization; Bloodwork & Frequency (00:07:20) Exercise, Zone 2 Cardio; Caloric Restriction (00:08:36) Intermittent Fasting, Growth Hormone, IGF-1 (00:11:05) Hormones & Sleep, Growth Hormone, Menopause, Andropause, TRT (00:13:28) Testosterone & Women, SHGB (00:15:19) Sponsor: Maui Nui (00:16:34) Dihydrotestosterone (DHT), Androgens; Turmeric & Black Pepper; Hair Loss (00:19:47) Polycystic Ovarian Syndrome (PCOS), Symptoms, Metformin, Inositol (00:23:13) Cannabis, Alcohol, Testosterone (00:24:48) Males & Testosterone, TRT, Prostate Cancer (00:26:04) Prolactin, Dopamine "Wave Pool", Tool: Casein & Gluten (00:27:23) Sponsor: Function (00:29:03) Social Relationships & Hormones, Tool: Planning for Crisis (00:31:02) Peptides, Growth Hormone & Risk; BPC 157, Sourcing & LPS (00:36:42) Melanotan, Uses & Risks (00:38:45) Spiritual Health, Interdisciplinary Health Integration (00:41:23) Caffeine & Hormones, Sleep; Acknowledgements Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices
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  • Welcome to Huberman Lab Essentials,

  • where we revisit past episodes for the most potent and actionable science-based tools for mental health,

  • physical health, and performance.

  • I'm Andrew Huberman and I'm a professor of neurobiology and ophthalmology at Stanford School of Medicine.

  • And now for my discussion about hormone health and optimization with Dr.

  • Kyle Gillette.

  • Dr.

  • Gillette, welcome.

  • Thank you for having me.

  • Well, I'm super excited to talk to you.

  • You are an encyclopedia of knowledge about hormone health for men and for women across the lifespan.

  • So I have many, many questions.

  • When someone comes to you as a patient, in terms of hormone health,

  • what are the sorts of probe questions that you ask and what are you looking for?

  • And I ask this

  • because I'd like people to be able to ask some of these very same questions for themselves.

  • So when you do a...

  • physical exam, and a history.

  • You have a lot of different parts.

  • You have your history of present illness.