Hello and welcome to Health Check from the BBC.
I'm Claudia Hammond.
Today we'll be asking how a person with a limb that's not working makes the decision to have it removed and replaced with a prosthetic.
I hear from the author of a new book on the artificial additions we might make to our bodies.
And the teachers in Iran providing mental health support to their pupils who've come to the country as refugees.
And to help me today, I have the BBC's Health and Science Correspondent, James Gallagher.
How are you?
I'm a little bit croaky, Claudia, but all the better for speaking to you.
Oh, it's the time of year, everyone's ill.
What do you have for us?
I have a story about a sperm donor who unknowingly harboured a mutation in his sperm that dramatically raised the risk of cancer for his children.
And he's had at least one hundred and...
97 of them across Europe.
It's an extraordinary story that.
Now before all that, since this is your last visit to health check in 2025,
you get the chance to tell us what you would select as your medical breakthrough of the year.
So what are you going to pick and why that breakthrough in particular?
I think it's an easy one for me, Claudia.
It's the first successful treatment for Huntington's disease.
And the reason I've picked this one is