A breakthrough in treating chronic pain

治疗慢性疼痛的重大突破

Health Check

2025-08-28

26 分钟
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One in five of us suffer with chronic pain globally and the exact cause of it is often unknown making it very hard to treat. However, in what has been hailed as a remarkable breakthrough, a gene has been identified that is critical for regulating pain signals. Professor David Bennett, head of Clinical Neurology at Oxford, who led the research explains. BBC Africa’s health correspondent Dorcas Wangira joins Claudia to delve into a decade-long research programme that found child mortality rates almost halved when poorer families in Kenya were given $1000 unconditionally. Chhavi Sachdev reports from India where government efforts to curtail rising rabies infections from stray dog bites has caused mass uproar. We explore the drivers behind a global wildfire paradox where scientists have observed a decline in the total area burned by fires but found the number of people exposed to wildfires has increased. Plus, Dorcas brings us the latest on the $9.7 million worth of contraceptives due to be destroyed after the scaling back of USAID. Presenter: Claudia Hammond Producer: Hannah Robins Assistant Producers: Katie Tomsett & Alice McKee
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  • Hello and welcome to Health Check from the BBC.

  • I'm Claudia Hammond and we have scoured the globe for the latest medical stories that we think you should know about.

  • In a moment,

  • could new genetic discoveries about the causes of chronic pain be a game changer when it comes to finding new non-addictive pain medication in the future?

  • And to help me today, I have BBC Africa's health correspondent, Dorcas Wangira.

  • How are you, Dorcas?

  • I'm fine.

  • Hi, Claudia.

  • And what do you have for us today?

  • We have a surprising study about wildfires and what the US decision to incinerate contraceptives means.

  • And from India, controversy over plans to round up stray dogs to prevent the spread of rabies.

  • First to a breakthrough which feels significant in the world of chronic pain.

  • It is estimated that one in five adults is trying to live their lives despite being hounded by pain.

  • And sometimes it's not clear from physical examinations why they're in such agony.

  • The causes have remained a mystery until now,

  • when scientists at the University of Oxford have identified a genetic cause which they hope could,

  • in the long run, lead to brand new drugs to treat chronic pain.

  • Now, this is a very new way of looking at this kind of pain.

  • I spoke to the head of the team, David Bennett,

  • who's professor of neurology and neurobiology at the University of Oxford.