Essentials: Effects of Fasting & Time Restricted Eating on Fat Loss & Health

基本要素:间歇性禁食和时间限制饮食对减脂与健康的效应

Huberman Lab

2025-08-28

43 分钟
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单集简介 ...

In this Huberman Lab Essentials episode, I explore intermittent fasting and time-restricted eating, highlighting the positive benefits for weight loss, metabolism, organ health, circadian rhythms and cellular repair. I explain a practical framework for designing a time-restricted eating window that aligns with your lifestyle, exercise schedule and social schedule. I also cover what breaks a fast, how to support fasting with tools like salt intake and post-meal walks, and the use of fasting-related supplements, including berberine and metformin. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Carbon: https://joincarbon.com/huberman LMNT: https://drinklmnt.com/huberman Joovv: https://joovv.com/huberman Timestamps (00:00) Intermittent Fasting, Time-Restricted Eating (TRE) (00:50) Diet, Weight Loss, Calories & Hormones (05:50) Body’s Response to Eating vs Fasting, Fasting Duration (09:04) Sponsor: Carbon (10:50) Time-Restricted Feeding & Metabolic Benefits, Circadian Gene Rhythm (16:19) Optimal Meal Timing, Tool: Extend Sleep-Related Fasts (21:29) Sponsors: AG1 & LMNT (24:02) Eating Window Length, Tools: Adjusting TRE for Building Muscle, Regularity (26:55) Accelerate Transition to Fasting, Glucose Clearing, Tool: After-Meal Walk (28:36) Metformin, Berberine, Continuous Glucose Monitors; Cell Growth vs Repair, mTOR (31:46) Gut Microbiome; Transitioning to Intermittent Fasting & Individualization (34:03) Tool: 8-Hour Feeding Window & Weight Loss (35:25) Sponsor: Joovv (36:40) What Breaks a Fast?, Sugar; Tool: Using Salt to Support Fasting (39:42) Tool: Ideal Feeding Window Guidelines; Exercise & Social Considerations Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices
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单集文稿 ...

  • Welcome to Huberman Lab Essentials,

  • where we revisit past episodes for the most potent and actionable science-based tools for mental health,

  • physical health, and performance.

  • I'm Andrew Huberman,

  • and I'm a professor of neurobiology and ophthalmology at Stanford School of Medicine.

  • What we're going to talk about today is how intermittent fasting,

  • aka time-restricted feeding, impacts weight loss.

  • fat loss in particular, muscle maintenance and loss and gain,

  • organ health, such as gut health and liver health,

  • the genome, the epigenome, inflammation, sickness, recovery,

  • and healing from sickness, exercise, cognition, mood, and lifespan.

  • So let's talk about eating and what happens when you eat,

  • and let's talk about fasting or not eating and what happens when you fast.

  • If ever there was a topic that is controversial,

  • especially on the internet, it is that of diet and nutrition.

  • So I'm wading into this with a smile and in eager anticipation of all the, but,

  • but, but this, and but, but that, and wait, but this showed that.

  • Here's the deal.

  • We need to precisely define what it is that we're talking about when we talk about nutrition.

  • I'm going to give you an example of a study.