Using AI to discover new antibiotics

利用人工智能发现新型抗生素

Health Check

2025-08-21

26 分钟
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单集简介 ...

AI models have helped to discover new potential antibiotics to treat drug resistant infections of gonorrhoea and MRSA. We speak to Professor Jim Collins from MIT to understand what’s next for his machine-generated medicines and the role AI could play in the future of drug discovery. A new report has found high rates of bloodstream infections and antibiotic resistance in central lines used in Indian ICUs. Family doctor Ann Robinson joins Claudia to understand the risks posed to already vulnerable patients. We consider a new review that found no evidence ketamine is effective at helping those with chronic pain, despite it being prescribed off-label for this use in some countries. Rwandan MPs have approved lowering the age adolescents can access sexual and reproductive health services without parental consent from 18 to 15. We catch up with BBC reporter Dorcas Wangira on what this could mean for the health of adolescents and the fallout of the decision in Rwanda. Finally, people with diabetes in India have long been told to steer clear of mangoes - Ann and Claudia unpick whether this advice needs to change. Presenter: Claudia Hammond Producer: Hannah Robins Assistant Producer: Katie Tomsett
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单集文稿 ...

  • This BBC podcast is supported by ads outside the UK.

  • Hello and welcome to Health Check from the BBC.

  • I'm Claudia Hammond and every week we dissect the latest findings, innovations and news in medicine.

  • Now in a moment,

  • how artificial intelligence has invented two brand new antibiotics to treat gonorrhoea after coming up with a whopping 36 million novel compounds.

  • And from Rwanda,

  • a new law to allow 15 to 17 year olds to obtain contraception without their parents' knowledge for the first time.

  • I have family doctor Anne Robinson in the studio.

  • How are you?

  • Hello, I'm fine, thank you.

  • What do you have for us today?

  • We're going to be talking about mangoes, the magnificent mango.

  • Excellent, I like them.

  • So more on that later on.

  • But we are starting with antibiotics.

  • Artificial intelligence has been harnessed in a brand new way to identify potential new drugs.

  • Researchers are focusing on two drug-resistant infections,

  • gonorrhoea and MRSA, or MRSA, as it's also known.

  • AI has invented 36 million compounds and two of those are showing real promise in the lab and in animals.

  • It is very early days, but could this be the way forward in the fight against antibiotic resistance?

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