Scientists test engineered microbes to fight disease; Has 1.5 degrees failed?; New theory why we’ve not found aliens

科学家测试经过基因改造的微生物以抗击疾病;1.5摄氏度的目标失败了吗?;为何我们尚未发现外星人,新理论揭晓

New Scientist Podcasts

2025-07-18

30 分钟
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单集简介 ...

Episode 312 People have been given genetically engineered microbes to prevent a common health condition - and it worked. The gut microbiome is now known to be associated with many health conditions - and in this case, the team managed to treat 9 people who get recurring kidney stones. With the gut’s links to mental health, cancer and more, could engineered microbes be used to treat more conditions in the future? Is 1.5C dead? It’s looking increasingly likely that we’re going to breach 1.5C of global warming - the goal set out in the Paris agreement. So do we need to set a new goal now? As scientists come up with alternative numbers to aim for, many are worried that moving the goalposts will kill climate ambition. But is there a middle ground that keeps everyone happy? Where are all the aliens? We may now have a solution to the famous Fermi paradox, which questions why we’ve never met anyone else in the universe, despite the existence of many Earth-like planets. And it’s all to do with tectonic plates - a geological phenomenon that may be rare outside of Earth, helping complex life to emerge on our planet.  Chapters: (00:39) Genetically modified gut microbes (07:03) Setting a new goal for global warming (17:20) Solving the Fermi paradox Hosted by Rowan Hooper and Penny Sarchet, with guests Grace Wade, Madeleine Cuff, Alex Wilkins, Ilana Seid, Robert Stern and Taras Gerya. To read more about these stories, visit https://www.newscientist.com/ Learn more about your ad choices. Visit megaphone.fm/adchoices
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单集文稿 ...

  • Hello and welcome to the World, the Universe and Us, the weekly news podcast from New Scientist.

  • I'm Dr Penny Sache.

  • And I'm Dr Rowan Hooper.

  • On today's show we discuss the controversial proposal that we abandon the 1.5 degrees target as the limit for global warming and instead set it at 1.7 degrees.

  • We're also going to hear about the earliest evidence for plate tectonics on Earth and find out how that influences the outcome of the Drake equation and that's the number of extraterrestrial civilisations in the Milky Way.

  • So that's the world and the universe and us.

  • Yeah, where's the us in our title?

  • Well this week we've got exciting news of how we could modify our microbiomes.

  • The gut microbiome has been implicated in everything from cancer to mental health and

  • as we've begun to understand this more deeply there's been this kind of tantalising question of can we use science to smartly improve and fine-tune our microbiota in a way to sort of prevent or even treat these diseases.

  • So this week there's news from a small trial that gave people genetically engineered microbes in an attempt to prevent kidney stones from forming.

  • Niche.

  • Well not actually.

  • stones affect one in 10 people apparently, so quite common.

  • Could this be the first step though, is the big question,

  • towards gene editing our microbiome and treating all kinds of things.

  • And Grace Wade is here to tell us more.

  • Hi. So what's really interesting about this study is that usually when researchers have tried to change people's gut microbiota,

  • they either focus on giving them naturally occurring gut bacteria or genetically modified bacteria.

  • But this usually doesn't work