Miracle drugs: genomic medicines are moving fast

奇迹药物:基因组药物正迅速发展

Editor's Picks from The Economist

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2024-08-08

9 分钟
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A handpicked article read aloud from the latest issue of The Economist. Today, gene-editing drugs can perform wonders—and are moving rapidly from lab to clinic. But they must overcome technical and economic hurdles. Listen to what matters most, from global politics and business to science and technology—subscribe to Economist Podcasts+ For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account.
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  • The Economist Hello, Alok Jha here.

  • I host Babbage, our science and tech podcast.

  • Welcome to Editor's Picks.

  • Here's an article handpicked from the latest edition of The Economist, read aloud.

  • I thought you might enjoy it.

  • One autumn day in 2020,

  • Patrick Doherty was walking his dog up a steep mountain in County Donegal,

  • Ireland, when he noticed he was unusually for him.

  • running out of breath.

  • The eventual diagnosis was terrifying.

  • Amyloidosis, a rare genetic disease that caused a protein,

  • amyloid, to build up in his organs and tissues.

  • The prognosis was even worse.

  • It would cause him years of pain until it finally killed him.

  • In the face of such terrible fortune, though, Mr. Doherty had a stroke of luck.

  • He was able to join a trial of a new medical therapy,

  • and with just a single injection, was apparently cured.

  • Now he continues to walk his dog up that steep mountain in County Donegal every week.

  • The treatment edited Mr. Doherty's genes using CRISPR-Cas9,

  • a technology that has moved from lab to clinic at lightning speed.