2025-02-27
39 分钟Welcome to Huberman Lab Essentials where we revisit past episodes for the most potent and actionable science based tools for mental health, physical health and performance.
I'm Andrew Huberman and I'm a professor of Neurobiology and Ophthalmology at Stanford School of Medicine.
This podcast is separate from my teaching and research roles at Stanford.
It is, however, part of my desire and effort to bring zero cost to consumer information about science and science related tools to the general public.
Today we're going to talk about how hormones impact feeding and hunger, as well as satiety, the feeling that you don't want to eat or that you've eaten enough.
Now, it's important to understand that hormones don't work alone in this context.
Today I'm going to describe some hormones that have powerful effects on whether or not you want to eat more or less or stop eating altogether.
But they don't do that on their own.
They do that in cooperation with the nervous system.
The first thing that you need to know about the nervous system side the neural control over feeding and hunger is that there's an area of your brain called the hypothalamus.
Now, the hypothalamus contains lots of different kinds of neurons doing lots of different kinds of things.
There's a particular area of the hypothalamus called the ventromedial hypothalamus, and it's one.
That researchers have been interested for a. Long time now in terms of its relationship to hunger and feeding.
And the reason is it creates these paradoxical effects.
What do I mean by that?
What they found was that sometimes lesioning or disrupting the neurons in the ventromedial hypothalamus would make animals or people hyperphagic.
They would want to eat like crazy.
And other lesions in other individuals or animals would make them anorexic.
It would make them not want to eat at all.
It would make food aversive.