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The Great Detectives Present Yours Truly Johnny Dollar (Old Time Radio)

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2025-01-31

28 分钟
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Introducing Predicting Diseases with Polygenic Risk Scores | Season 2 Episode 2 from Tomorrow's Cure. Follow the show: Tomorrow's Cure Imagine knowing your risk for disease long before symptoms appear. With early detection and targeted interventions, this knowledge could transform how complex healthcare challenges are addressed. Researchers are now leveraging genetic data to enhance disease risk prediction through an innovative tool known as a polygenic risk score. The episode features Victor Ortega, M.D., Ph.D., associate director of the Mayo Clinic Center for Individualized Medicine and Louise Wain, Ph.D., professor of respiratory research, University of Leicester.  DISCLAIMER: Please note, this is an independent podcast episode not affiliated with, endorsed by, or produced in conjunction with the host podcast feed or any of its media entities. The views and opinions expressed in this episode are solely those of the creators and guests. For any concerns, please reach out to team@podroll.fm.
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  • I'm Dr. Sanjay Gupta, host of the Chasing Life podcast.

  • People are often asked, are they glass half empty or glass half full sort of people?

  • Are some people just born happier than others?

  • And what might they be doing that the rest of us aren't?

  • What if any are the universal keys to happiness?

  • Listen to Chasing Life, streaming now wherever you get your podcasts.

  • If someone you love has faced heart or lung disease,

  • you might find yourself wondering, does that mean you're at risk too?

  • It's a common concern for many of us.

  • What I've learned is there's no single gene responsible for most diseases.

  • There are a lot of different genetic variants at play,

  • along with your personal habits and environment that determine the risk of developing a disease.

  • Well now,

  • scientists are developing a new tool that can help us understand whether our genes might predispose us to certain diseases or elevate our risk.

  • It's called a Polygenic Risk Score, or PRS.

  • That's what we'll be diving into today.

  • Joining us, Dr. Victor Ortega.

  • He's an associate director of the Mayo Clinic Center for Individualized Medicine.

  • He's also a pulmonologist or a lung specialist, as well as a genomic scientist at Mayo Clinic.

  • I think that one day we're going to go into a doctor's office to get our heart rate,