Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

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  Welcome to Huberman Lab Essentials, where we revisit past episodes for the most potent

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  and actionable science-based tools for mental health, physical health, and performance.

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  I'm Andrew Huberman, and I'm a professor of neurobiology and ophthalmology at Stanford School of Medicine.

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  And now for my discussion with Dr. Nolan Williams.

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  Thanks for joining today.

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  I'm really excited to have this conversation.

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  I have a lot of questions about different compounds, psychedelics in particular.

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  But before we get into that discussion, I want to ask you about depression, broadly speaking.

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  I heard you say in a wonderful talk that you gave that depression is perhaps the most debilitating condition worldwide.

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  Yet in contrast to other medical conditions like cancer,

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  we actually have a fairly limited number of tools to approach depression.

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  And yet the number of tools and the potency of those tools is growing.

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  Depression is the most disabling condition worldwide.

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  What's interesting about depression is it's both a risk factor for other illnesses

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  and it makes other medical and psychiatric illnesses worse.

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  So recently, the American Heart Association added depression

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  as the fourth major risk factor for coronary artery disease.

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  So alongside the risk factors that we know, hypertension, high blood pressure, hyperlipidemia, high cholesterol.

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  And diabetes, high blood sugar, those three have been on the list for a long time,

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  and depression ends up being added to the list as the fourth one.

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